Immunologic homology of human blood group glycosyltransferases and genetic background of blood group (ABO) determination
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چکیده
منابع مشابه
Immunologic homology of human blood group glycosyltransferases and genetic background of blood group (ABO) determination.
The human blood groups (ABO) are known to be determined by the terminal carbohydrate residues attached to common carbohydrate chains of the red cell surface. Specific transferases, i.e., N-acetylgalactosaminyltransferase (A enzyme) in blood group A persons and galactosyltransferase (B enzyme) in blood group B persons. are responsible for transferring the carbohydrates to the terminal galactose ...
متن کاملHuman Blood Group Glycosyltransferases
An N-acetylgalactosaminyltransferase, which converts blood group 0 red blood cells to A cells, was purified to homogeneity from plasma of blood group A, subjects. The enzyme was adsorbed on Sepharose QB, and after washing out the impurities, the enzyme was eluted with UDP. This procedure resulted in a 70,000to lOO,OOO-fold increase in specific activity with recovery of about 80%. Further purifi...
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Background Several factors may cause infertility and fetal loss. Blood groups antigens seem to be implied in the mechanisms of infertility and fetal loss. Maternal natural antibody can react against father’s blood group antigens on spermatozoa. The effects of parental blood group system on infertility and fetal surveillance perceived by its manifestation in prezygotic (caused infertility) and ...
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Objectives: The saliva was first analyzed for the presence of anti-A and anti-B hemagglutinins in 1928. However, it was not been utilized as evidence in criminal investigations because of insufficient techniques available at that time. Hence, the present study was designed to evaluate feasibility of ABO group in medicolegal cases by determining the efficacy and accuracy of ABO blood group deter...
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Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to in...
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ژورنال
عنوان ژورنال: Blood
سال: 1979
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v54.2.344.344